Soil is the main natural resource for human survival and development. In recent years, the aquatic risks of tire rubber antioxidant N-(1, 3-dimethylbutyl-N""-phenyl-p-phenylenediamine (6PPD) and its ozonated product N-(1, 3-dimethylbutyl-N"" -phenyl-p-benzoquinone (6PPD-Q) have attracted global attention, but little is known about their soil environmental behavior and soil biota effects. Research has shown that soil is an important "aggregation" of tire wear particles, and the TWPs entering the environment release various of additives, such as rubber antioxidants, silica, metals, etc. Among them, p-Phenylenediamines(PPDs) are the most widely added rubber antioxidants due to their excellent performance, which can be released as TWPs entered environmental media and produced derivatives such as PPD-Qs. Therefore, studying the fate and ecological environmental risks of 6PPDs and their derivatives in soil is of great significance. This article focuses on soil environmental safety and ecological health, stating the behavioral characteristics of the occurrence, migration, and transformation of 6PPD and 6PPD-Q in the soil environment. For providing a theoretical basis of the ecological risk assessment and prevention and control of 6PPD and 6PPD-Q pollution, this paper introduces the accumulation, transportation, and metabolic mechanisms of 6PPD and 6PPD-Q in soil organisms, and elaborates on their toxic effects and mechanisms on soil organisms.