In view of the particularity of the environmental conditions and management model,of the Tarim desert highway shelter forest,and the important roles of the forest in development of the socio economy of South Xinjiang,an experiment was carried out using sampled soils from four layers,0~5 cm,5~15 cm,15~30 cm,30~50 cm,in the forest lands dripirrigated with ground water,2.58,5.75,8.90 and 13.99 g/L^-1 in minera lization degree,respectively.Results showth at there are obvious canonical correlation variab les between soil nutrient,microbe quantity and enzyme activity,which basically represents general correlation between variables;the correlation between soil nutrients and soil microbial biomass is mainly attributed to total N,available N,organic matter,total P of nutrient factors and actinomycetes quantity,microbial biomass C and microbial biomass P,while the correlation between soil nutrients and soilenzyme activity is to organic carbon,available K of soil nutrient factors and catalase activity,phosphatase activity of soil enzyme activity factors;and the correlation between soil microbial biomass and soil enzyme activity is to microb ial biomass P,microbial biomass N,invertase activity,and phosphatase activity of soil enzymes Moreover,vertical differences between these three groups of comprehensive factors were found So,the effects of mineralization degree of ground water used as irrigation water on soil nutrients and microbial biomass in the Tarim desert highway shelter forest land are remarkab le,and ground water,high in mineralization degree goes against soil nutrien taccumulation and microbe survival.