PCB contamination levels of farmland soil and vegetables in the surroundings of E-waste contaminated areas were investigated and the risks to human health in these areas were assessed. The investigation findings show that the average PCB concentrations in soil and vegetables were 6.78~15.48 μg kg^-1 and 5.98~130.70 μg kg^-1 respectively. Compared with the background level of Tibet, West China, and the PCB contamination level in the rural farmland of Zhejiang Province, there exists high accumulations of PCBs in the farmland surrounding E-waste areas. The health risk assessment based on the comparative analysis of soil and vegetables pollution resulting from the exposure to food chain indicates that cancer risk in one’s lifetime is 6.50×10^-6~1.24×10^-4, which is one to three order of magnitude higher than the standard concentration level. It is suggested from vegetable samples that the non-carcinogenic risk level for some farmlands is higher than the acceptable level (HQ=1). It is concluded that in the stated area PCB concentration in the farmland ecological system has posed a major risk to human health.