Abstract:【Objective】Triclosan (TCS) and triclocarban (TCC), are typical pharmaceutical and personal care products (PPCPs) that are extensively detected in soil, posing potential risks of raising soil microbes’ drug resistances and inhibiting soil respirations. However, so far little is known about their influences on soil gross N transformation processes and N2O emissions in soil. 【Method】 In view of this, an indoor incubation experiment was carried out using the 15N diluting-enriching method coupled with a N transformation numerical model to investigate influences of TCS and TCC, applied alone or in combination, at varying rates on preliminary N transformation rate and N2O release rate in paddy soil. 【Result】Results show that the treatment of applying 1 mg·kg-1 TCC or 5 mg·kg-1 TCS+2 mg·kg-1 TCC did not have much influence on N mineralization-assimilation in the paddy soil, but all the other treatments did quite reversely (P < 0.05). Besides, all the TCC and TCS treatments significantly inhibited autotrophic nitrification, microbial immobilization of nitrate and dissimilatory nitrate reduction to ammonium (Dissimilatory nitrate reduction to ammonium, DNRA), except for the treatment of applying 2 mg·kg-1 TCS or 5 mg·kg-1 TCS+2 mg·kg-1 TCC. It is noteworthy that all the treatments (P< 0.05) increased cumulative emission of N2O significantly or by 1.13~1.44 folds as compared with the control. 【Conclusion】All the findings in this study suggest that TCS and TCC alter aerobic N transformation processes, which may bring about adverse effects on N recycling in the paddy field ecosystem, and promote N2O emission, which may enhance the potential contribution of the paddy field ecosystem to greenhouse effect and damage of the ozone layer. Therefore, in evaluating soil ecological risks of TCS and TCC in future, it is essential to take into account their potential influences on N transformation and N2O emission.