A study was carried out on variation of fresh weight of a whole leaf and contents of water, soluble sugar, polysaccharide and aloin in leaves of aloes after four years of irrigation with mixtures of seawater and fresh water different in mixing ratio. Results show that no distinct difference was observed between irrigations with 0%, 10% and 25% of seawater in leaf fresh weight, between irrigations with 0%, 10%, 25%, 50% and 75% of seawater in leaf dry weight, and between irrigations with 0%, 10%, 25% and 50% of seawater in water content in the ground part of aloe, and that irrigations with 50%, 75% and 100% of seawater reduced leaf fresh weight by 11.5%, 28.1% and 45.6%, respectively as compared with control (0% seawater), irrigation with 100% of seawater did leaf dry weight by 14%, and irrigations with 75% and 100% of seawater water contents in the ground part significantly.Among the leaves different in position, water content in leaves dropped with intensifying seawater stress, and the effect was more significant in leaves of the lower part than in leaves of the middle and upper parts.Soluble sugar content in leaves of aloe irrigated with seawater increased with the rising seawater ratio. Polysaccharide content in leaves did not vary much with the irrigation Aloin content increased significantly with the rising seawater ratio of the irrigation and peaked in aloe irrigated with 75% of seawaterTherefore, it is concluded that the experiment is successful and that irrigating Aloe vera with mixture of seawater and fresh water of a proper ratio (75%) can save fresh water sources and markedly improve the content of aloin, which is the major element of medicinal effect in aloe.