The key to ecological restoration of rocky desertification is to recover vegetation, of which the nature is to improve soil productivity. With a tract of farmland on the slope of depression in between typical karst hills as control, integrated ecological effect of the practice of “Grain for Green” was analyzed by determining 21 soil indexes of seven models of “Grain for Green”, i.e. converting farmland to land of Zenia insignis, Toona sinensis, Castanea mollissima, Citrus reticulata, Zenia insignis + Guimu No. 1 Forage, Guimu No. 1 Forage, or desertion for comparison with those of the control. On such a basis, an optimal model was screened out. Results show that in comparison with red soil in regions at the latitude, the soil in karst depression was higher in soil nutrient except for total potassium and available phosphorus. The practice of “Grain for Green” significantly increased most of the soil main nutrients, soil water content, and mineral nutrients, but reduced the content of SiO₂, indicating that all the seven models, except for cultivation of Zenia insignis, had their nutrient status restored up to the pre-rocky desertification level. Besides, the practice also increased microbial population, B_C, B_C/SOM, and B_C/TN, but decreased slightly B_N and B_N/TN. Clustering analysis intuitively divided the slope field and 7 conversion models into 4 types, i.e. remarkable improvement, improvement, slow improvement, and sluggish improvement, and the models of cultivation of Toona sinensis and Castanea mollissima are best in soil ecological effects.