【Objective】The aim of this work is to investigate 1）whether the amendment of cinnamic acid could mitigate the incidence of Fusarium wilt and 2）how wheat and faba bean intercropping alleviates cinnamic acid autotoxicity. 【Method】A pot experiment was conducted on wheat and faba bean intercropping and amendment of cinnamic acid at a varying rate (C0（0.0 mg kg^-1），C1（14.0 mg kg^-1），C2（28.0 mg kg^-1） and C3（56.0 mg kg^-1）). 【Result】1) In comparison with Treatment C0, amendment of cinnamic acid decreased the activity of peroxidase (POD), but significantly increased the content of malondialdehyde (MDA), thus leading to disorder of metabolic and physiological functions and aggravation of the damage of membrane lipid by peroxidation in the treatments under monocropping of faba bean．2) The amendment of cinn-amic acid decreased the average well color development (AWCD), Shannon-Wiener diversity index (H) and substrate richness (S), thus altering soil microbe community structure in faba bean rhizosphere, by increasing the number of Fusarium oxysporum; and increasing the incidence index of faba bean Fusarium wilt. As a result, dry weight of the root system of monocropped faba bean decreased. 3) Among the treatments amended with cinnamic acid at the rate of C1, C2 and C3, the treatments of intercropped faba bean, were 22.4%, 81.0% and 100.0% higher in POD activity of faba bean, and 45.1%, 92.4% and 145.1% lower in MDA content than their corresponding ones of monocropped faba bean. 4) Treatments C1 and C2 of intercropped faba bean were 110.5% and 83.9% higher in total carbon utilization ability than their corresponding ones of monocropped faba bean, especially in utilization of carbohydrates, amino acids, and carboxylic acids. Besides, they were also much higher in Shannon-Wiener diversity index and substrate richness, had soil microbe community structure in the rhizosphere significantly changed by decreasing the population of Fusarium oxysporum in the faba bean rhizosphere by 16.7%~20.2% and 41.1%~51.8%, and increased root dry weight by 11.3%~23.6% and 72.9%~154.9%, respectively. 【Conclusion】Intercropping of faba bean with wheat significantly increases physiological resistance of faba bean to Fusarium oxysporum f. fabae, and significantly lowers the incidence of Fusarium wilt on one hand and effectively regulates soil microbial activity and diversity in the faba bean rhizosphere soil, on the other, thus alleviating the harm of Fusarium wilt caused by cinnamic acid and promoting growth of the crop. However, the effect is affected by concentration of cinnamic acid. By making use of the allelopathic effect of wheat as non-host crop, the intercropping of faba bean with wheat is an effective measure to alleviate autotoxicity of cinnamic acid.