How to take scientific and effective countermeasures to prevent and remediate soil contamination, so as to ensure the quality and safety of agricultural products, has become a great public concern in China. This paper illustrated the status and functions of soil in the new era; reviewed the progress in research and development on agricultural soil contamination control and remediation. Furthermore, the strategic focus and technical approach for science and technologies on soil contamination prevention, control and remediation, along with their industrial applications, were proposed to promote the green and high-quality agricultural development.