Influences of six organic pollutants (styrene, m-dichlorobenzene, o-Dichlorobenzene, Chllotobenzene, Dibutyl phthalate, and Hexadecane) on pure culteureced Azotobdcter claroococrzm and Cellzrlomonas sp., as well as on actinomycetes, molds and yeasts in the soil were studied. These microbes were collected, isolated and identified by the authors from the upland soils irrigated with the water from the Datong river in Chang}zhou region of Jiangsu province. The experiment data were processed by the means of variance analysis in order to get rid of the disturbance of the experimental errors and make more reliable analysis. The results ahowed that these pollutants had different effects on different microbes at concentrations of both lOppm and 50ppm: they either decrease the counts of Azorobacter clarococczzm, Cellzzlomonas sp. and actinomycetes or increase the counts of molds and yeasts, otherwise they had no significant effect on soil microbes. Among these effects Cellzzlomoszas sp. could not be alive after dibutyl phthalate treatment at concentrations of 10 ppm and 50 ppm.