Reports of groundwater contamination by several pesticides have increased in recent years. In this work, one model in terms of pesticides' potential to leach through the crop root zone and to intrude into grounderwater was established to evaluate the potential of pesticide groundwater contamination with soil characteristics, regional climate and pesticide properties as its running parameters. The results showed that paclobutrazol was more likely to contaminate groundwater than dimehypo, but trifluralin was very unlikely. Groundwater in red soil region was very likely contaminated by pesticides. In case of rice planting, the potential threat of pesticide groundwater contamination increased.