To aim directly at problem of crop demanding boron in sustainable agriculture development of brown-red soil in the hilly region of south Hubei Province, the content, forms, distribution, annual change, runoff, leaching and balance of the boron were analyzed. On the base of the synthetic analysis, the simulation model of boron cycling was set up. The results showed that distribution, removing and cycling of boron in different type farmland were different in the typical catchment, the period of annual change of majority form boron is six months, the surface assembled of HWSB is obvious, but the vertical transfer coefficient of HWSB was different in different type farmlands, boron loss of runoff and leaching were affected by leaves area index and stable leaching ratio principally.